New automatic algorithm for segmentation of myocardial scar in both inversion recovery and phase sensitive inversion recovery late gadolinium enhancement: validation against TTC and in multi-center, multi-vendor patient data
نویسندگان
چکیده
New automatic algorithm for segmentation of myocardial scar in both inversion recovery and phase sensitive inversion recovery late gadolinium enhancement: validation against TTC and in multi-center, multi-vendor patient data Jane Tufvesson, Robert Jablonowski, Henrik Engblom, Marcus Carlsson, Anthony H Aletras, Pavel Hoffmann, Alexis Jacquier, Frank Kober, Bernhard Metzler, David Erlinge, Dan Atar, Håkan Arheden, Einar Heiberg
منابع مشابه
A new automatic algorithm for quantification of myocardial infarction imaged by late gadolinium enhancement cardiovascular magnetic resonance: experimental validation and comparison to expert delineations in multi-center, multi-vendor patient data.
BACKGROUND Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) using magnitude inversion recovery (IR) or phase sensitive inversion recovery (PSIR) has become clinical standard for assessment of myocardial infarction (MI). However, there is no clinical standard for quantification of MI even though multiple methods have been proposed. Simple thresholds have yielded varying ...
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Background The dual inversion recovery (dual IR) pulse sequence has recently been shown to improve blood suppression and infarct delineation in late gadolinium enhancement (LGE) images of myocardial infarction. This resulted in significantly lower inter-observer variability in manual outlining of scar and higher expert confidence in scar detection and transmurality when compared with convention...
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Background Cardiac magnetic resonance (CMR) imaging using phase sensitive inversion recovery (PSIR) late gadolinium enhancement (LGE) is the in vivo reference standard for assessing focal myocardial scar. Post-contrast T1-mapping by Modified Look-Locker Inversion recovery (MOLLI) can be used to generate a Synthetic PSIR LGE (SynLGE) image with an image contrast similar to conventional LGE image...
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Background Myocardial scar volume quantification has been shown to predict response to medical, surgical, and device therapy. Phase sensitive inversion recovery (PSIR)-based Late Gadolinium Enhancement (LGE) image reconstruction is clinically attractive for its reduced dependence on accurate prescription of the Time from Inversion (TI time), and is becoming a preferred approach for many centers...
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BACKGROUND Myocardial infarction (MI) can be readily assessed using late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR). Inversion recovery (IR) sequences provide the highest contrast between enhanced infarct areas and healthy myocardium. Applying such methods to small animals is challenging due to rapid respiratory and cardiac rates relative to T1 relaxation. METHODS He...
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